PRESENTATION: Tramadol 37.5 mg + Paracetomol 325 mg Tablets 

DRUG CLASS: Opioid analgesic and Anti pyretic 

MECHANISM OF ACTION: 

Tramadol  : Tramadol inhibits the reuptake of the natural neurotransmitters norepinephrine (noradrenaline) and serotonin, and also binds weakly to μ-opioid receptors, blocking the transmission of pain signals to the brain.

Tramadol is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine. Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain. It is considered a Step 2 option on the World Health Organization's pain ladder and has about 1/10th of the potency of morphine.

Paracetamol : Paracetamol is an analgesic (pain reliever) and an anti-pyretic (fever reducer) which works by blocking the release of certain chemical messengers that cause fever and pain.

INDICATIONS:  I[s indicated for the management of moderate to moderately severe chronic pain in adults who require around-the clock treatment of their pain for an extended period of time.

DOSAGE :  As Directed by the Physician