PRESENTATION: Pioglitazone 7.5/15

DRUG CLASS: Thiazolidinediones

MECHANISM OF ACTION: 

Pioglitzone : Pioglitazone is a potent and selective agonist for peroxisome proliferator-activated receptor-gamma (PPARgamma).

Activation of nuclear PPARgamma receptors influences the production of a number of gene products involved in glucose and lipid metabolism.

PPARgamma is abundant in the cells within the renal collecting tubules; fluid retention results from stimulation by thiazolidinediones which increases sodium reabsorption.

INDICATIONS & DOSAGE: As Directed by the Physician