PRESENTATION: Glibenclamide 5mg + Metformin 850mg SR 

DRUG CLASS: Sulfonylurea (Glyburide) & Biguanide (Metformin) 

MECHANISM OF ACTION:  

Glibenclamide : Stimulates insulin release from the pancreatic beta cells; reduces glucose output from the liver; insulin sensitivity is increased at peripheral target sites

Metformin decreases hepatic glucose production, decreasing intestinal absorption of glucose and improves insulin sensitivity (increases peripheral glucose uptake and utilization)

INDICATIONS & DOSAGE: As Directed by the Physician